Wednesday, May 26, 2004
Sleep-related hypoglycemia-associated autonomic failure in type 1 diabetes
Entrez PubMed: "Sleep-related hypoglycemia-associated autonomic failure in type 1 diabetes: reduced awakening from sleep during hypoglycemia."
Given that iatrogenic hypoglycemia often occurs during the night in people with type 1 diabetes, we tested the hypothesis that physiological, and the resulting behavioral, defenses against developing hypoglycemia-already compromised by absent glucagon and attenuated epinephrine and neurogenic symptom responses-are further compromised during sleep in type 1 diabetes. To do so, we studied eight adult patients with uncomplicated type 1 diabetes and eight matched nondiabetic control subjects with hyperinsulinemic stepped hypoglycemic clamps (glucose steps of approximately 85, 75, 65, 55, and 45 mg/dl) in the morning (0730-1230) while awake and at night (2100-0200) while awake throughout and while asleep from 0000 to 0200 in random sequence. Plasma epinephrine (P = 0.0010), perhaps norepinephrine (P = 0.0838), and pancreatic polypeptide (P = 0.0034) responses to hypoglycemia were reduced during sleep in diabetic subjects (the final awake versus asleep values were 240 +/- 86 and 85 +/- 47, 205 +/- 24 and 148 +/- 17, and 197 +/- 45 and 118 +/- 31 pg/ml, respectively), but not in the control subjects. The diabetic subjects exhibited markedly reduced awakening from sleep during hypoglycemia. Sleep efficiency (percent time asleep) was 77 +/- 18% in the diabetic subjects, but only 26 +/- 8% (P = 0.0109) in the control subjects late in the 45-mg/dl hypoglycemic steps. We conclude that autonomic responses to hypoglycemia are reduced during sleep in type 1 diabetes, and that, probably because of their reduced sympathoadrenal responses, patients with type 1 diabetes are substantially less likely to be awakened by hypoglycemia. Thus both physiological and behavioral defenses are further compromised during sleep. This sleep-related hypoglycemia-associated autonomic failure, in the context of imperfect insulin replacement, likely explains the high frequency of nocturnal hypoglycemia in type 1 diabetes.
posted by Anonymous
PermaLink @ 1:32 PM 0 comments
Given that iatrogenic hypoglycemia often occurs during the night in people with type 1 diabetes, we tested the hypothesis that physiological, and the resulting behavioral, defenses against developing hypoglycemia-already compromised by absent glucagon and attenuated epinephrine and neurogenic symptom responses-are further compromised during sleep in type 1 diabetes. To do so, we studied eight adult patients with uncomplicated type 1 diabetes and eight matched nondiabetic control subjects with hyperinsulinemic stepped hypoglycemic clamps (glucose steps of approximately 85, 75, 65, 55, and 45 mg/dl) in the morning (0730-1230) while awake and at night (2100-0200) while awake throughout and while asleep from 0000 to 0200 in random sequence. Plasma epinephrine (P = 0.0010), perhaps norepinephrine (P = 0.0838), and pancreatic polypeptide (P = 0.0034) responses to hypoglycemia were reduced during sleep in diabetic subjects (the final awake versus asleep values were 240 +/- 86 and 85 +/- 47, 205 +/- 24 and 148 +/- 17, and 197 +/- 45 and 118 +/- 31 pg/ml, respectively), but not in the control subjects. The diabetic subjects exhibited markedly reduced awakening from sleep during hypoglycemia. Sleep efficiency (percent time asleep) was 77 +/- 18% in the diabetic subjects, but only 26 +/- 8% (P = 0.0109) in the control subjects late in the 45-mg/dl hypoglycemic steps. We conclude that autonomic responses to hypoglycemia are reduced during sleep in type 1 diabetes, and that, probably because of their reduced sympathoadrenal responses, patients with type 1 diabetes are substantially less likely to be awakened by hypoglycemia. Thus both physiological and behavioral defenses are further compromised during sleep. This sleep-related hypoglycemia-associated autonomic failure, in the context of imperfect insulin replacement, likely explains the high frequency of nocturnal hypoglycemia in type 1 diabetes.
posted by Anonymous
PermaLink @ 1:32 PM 0 comments
Krispy Kreme details plans to meet low-carb challenge
EMERY P. DALESIO
Associated Press
Krispy Kreme details plans to meet low-carb challenge
WINSTON-SALEM, N.C. - Krispy Kreme Doughnuts is prepared to adapt to the low-carb dieting phenomenon it blames for a drop in sales of their sugary snacks, the company's top executive said Wednesday.
'The way we're looking at it is we're going to assume that it is' here to stay, Scott Livengood, chief executive officer of the doughnut-maker, said at the company's annual meeting. 'And we make our plans and do things in a, call it a worst case scenario. I think there is always a real possibility that people are going to decide a balanced lifestyle is appropriate for them and the dynamics will change again.
'But on the other hands we're not going to take anything for granted.'
Krispy Kreme reported Tuesday that it lost $24.4 million in the first quarter, its first quarterly loss since going public in 2000. The company's stock has fallen by about a third in the past month.
The company will continue expanding overseas, operate more efficiently and introduce new products to attract customers who aren't going low-carb, Krispy Kreme executives told the about 220 shareholders who came to the meeting. Most seemed sympathetic to the challenges facing the company.
Grocery stores will start selling bags of Krispy Kreme coffee to brew at home and the company's doughnut shops will start selling a low-sugar doughnut and frozen drinks this year.
Overseas expansion will "
posted by Anonymous
PermaLink @ 11:58 AM 0 comments
Associated Press
Krispy Kreme details plans to meet low-carb challenge
WINSTON-SALEM, N.C. - Krispy Kreme Doughnuts is prepared to adapt to the low-carb dieting phenomenon it blames for a drop in sales of their sugary snacks, the company's top executive said Wednesday.
'The way we're looking at it is we're going to assume that it is' here to stay, Scott Livengood, chief executive officer of the doughnut-maker, said at the company's annual meeting. 'And we make our plans and do things in a, call it a worst case scenario. I think there is always a real possibility that people are going to decide a balanced lifestyle is appropriate for them and the dynamics will change again.
'But on the other hands we're not going to take anything for granted.'
Krispy Kreme reported Tuesday that it lost $24.4 million in the first quarter, its first quarterly loss since going public in 2000. The company's stock has fallen by about a third in the past month.
The company will continue expanding overseas, operate more efficiently and introduce new products to attract customers who aren't going low-carb, Krispy Kreme executives told the about 220 shareholders who came to the meeting. Most seemed sympathetic to the challenges facing the company.
Grocery stores will start selling bags of Krispy Kreme coffee to brew at home and the company's doughnut shops will start selling a low-sugar doughnut and frozen drinks this year.
Overseas expansion will "
posted by Anonymous
PermaLink @ 11:58 AM 0 comments
Tuesday, May 18, 2004
KRCG.com - Wendy's-Low Carb
KRCG.com - Wendy's-Low Carb: "Wendy's-Low Carb
4/27/2004, Dublin, Ohio
Wendy's is testing the low-carb market by
offering bunless 'sandwiches' at 248 of the fast-food chain's restaurants in six U-S- cities.
Those cities include Kansas City and St. Josephi in Missouri, and Wichita in Kansas.
A Wendy's official says that the fast-food chain is creating choices for people watching their carbohydrate intake.
The meals feature either a cheeseburger or grilled chicken breast on a bed of Romaine lettuce, topped with slices of tomato
and red onion; a Caesar side salad; and a medium Diet Coke.
The cheeseburger meal has six grams of carbs, while the grilled
chicken meal has eight.
Test market locations include Tulsa, Okla.; Virginia Beach, Va.; Salt Lake City; Kansas City and St. Joseph, Mo.; and Wichita, Kan"
posted by Anonymous
PermaLink @ 8:39 AM 0 comments
4/27/2004, Dublin, Ohio
Wendy's is testing the low-carb market by
offering bunless 'sandwiches' at 248 of the fast-food chain's restaurants in six U-S- cities.
Those cities include Kansas City and St. Josephi in Missouri, and Wichita in Kansas.
A Wendy's official says that the fast-food chain is creating choices for people watching their carbohydrate intake.
The meals feature either a cheeseburger or grilled chicken breast on a bed of Romaine lettuce, topped with slices of tomato
and red onion; a Caesar side salad; and a medium Diet Coke.
The cheeseburger meal has six grams of carbs, while the grilled
chicken meal has eight.
Test market locations include Tulsa, Okla.; Virginia Beach, Va.; Salt Lake City; Kansas City and St. Joseph, Mo.; and Wichita, Kan"
posted by Anonymous
PermaLink @ 8:39 AM 0 comments
Monday, May 17, 2004
Tulsans Test Wendy's New Low Carb Specials
Wendy's is going low-carb and Tulsa is testing the market for the fast-food chain.
Wendy's is now offering Meals for Carb Counters. Customers can choose from a 6 low-carb bunless cheeseburger meals, or a grilled chicken meal with eight grams of carbs.
Burger King, Hardee's and Carl's Junior also offer bunless burgers. And McDonald's is phasing out its "super-sizes" and introducing "Go Active" healthier Happy Meals.
Alan Rowan with Wendy's:
posted by Unknown
PermaLink @ 5:13 PM 0 comments
Wendy's is now offering Meals for Carb Counters. Customers can choose from a 6 low-carb bunless cheeseburger meals, or a grilled chicken meal with eight grams of carbs.
Burger King, Hardee's and Carl's Junior also offer bunless burgers. And McDonald's is phasing out its "super-sizes" and introducing "Go Active" healthier Happy Meals.
Alan Rowan with Wendy's:
More and more customers are requesting to have low carb alternatives, and Tulsa was chosen - one of six cities to be a part of the test from Wendy's to try to see how the meals work as a whole.
posted by Unknown
PermaLink @ 5:13 PM 0 comments
Friday, May 07, 2004
Arby's Carb
Arby's® Low Carbys LTO (Limited Time Only) Items
Description----------------------Total Carbs-----------D. Fiber------------Net Carbs
Low Carbys:
Roast Ham & Swiss----------------5--------------------<1---------------------5
Roast Turkey & Swiss-------------4--------------------<1----------------------4
Roast Beef & Swiss----------------3----------------------1----------------------2
Roast Turkey Ranch & Bacon----5--------------------<1----------------------5
Ultimate BLT--------------------------6----------------------1---------------------5
Regular Roast Beef-----------------1--------------------<1----------------------1
Giant Roast Beef-------------------1---------------------<1--------------------1
Big Montana®----------------------1-----------------------1---------------------0
Beef n' Cheddar--------------------1---------------------<1--------------------1
Super Roast Beef------------------2-----------------------1---------------------1
French Dip n' Swiss---------------1----------------------<1-------------------1
Chicken Breast Fillet-------------15---------------------<1-------------------15
Chicken Bacon n' Swiss---------16---------------------<1-------------------16
posted by Anonymous
PermaLink @ 11:06 AM 0 comments
Description----------------------Total Carbs-----------D. Fiber------------Net Carbs
Low Carbys:
Roast Ham & Swiss----------------5--------------------<1---------------------5
Roast Turkey & Swiss-------------4--------------------<1----------------------4
Roast Beef & Swiss----------------3----------------------1----------------------2
Roast Turkey Ranch & Bacon----5--------------------<1----------------------5
Ultimate BLT--------------------------6----------------------1---------------------5
Regular Roast Beef-----------------1--------------------<1----------------------1
Giant Roast Beef-------------------1---------------------<1--------------------1
Big Montana®----------------------1-----------------------1---------------------0
Beef n' Cheddar--------------------1---------------------<1--------------------1
Super Roast Beef------------------2-----------------------1---------------------1
French Dip n' Swiss---------------1----------------------<1-------------------1
Chicken Breast Fillet-------------15---------------------<1-------------------15
Chicken Bacon n' Swiss---------16---------------------<1-------------------16
posted by Anonymous
PermaLink @ 11:06 AM 0 comments
Tuesday, May 04, 2004
Carb Counting at Sonic
Provider---Description-------------------------------------Total Carbs-----------Net Carbs
Sonic------ Carb Friendly Tortilla------------------------------30---------------------15
Sonic------Carb Friendly Chicken Club Wrap---------------34---------------------18
Sonic------Diet Cherry Limeade - Large----------------------8-----------------------6
Sonic------Lime Wedge (each)---------------------------------2-----------------------1
Sonic------Cherry (each)----------------------------------------2-----------------------2
Sonic------No. 1 Sonic Burger---------------------------------43---------------------41
Sonic------No. 2 Sonic Burger---------------------------------43---------------------41
Sonic------No. 1 Sonic Cheeseburger-----------------------44----------------------42
Sonic------No. 2 Sonic Cheeseburger-----------------------44----------------------42
Sonic------Jr. Burger--------------------------------------------27-----------------------26
Sonic------Bacon Chedder Burger----------------------------60---------------------56
Sonic------Chicken Club Wrap---------------------------------75---------------------72
Sonic------Country Fried Steak Sandwich-------------------56---------------------54
Sonic------Chicken Strip Dinner-------------------------------86---------------------81
Sonic------Chicken Strip Snack--------------------------------22---------------------22
Sonic------Cherry Limeade - Large---------------------------96---------------------94
Sonic------Grilled Chicken Wrap------------------------------40---------------------38
Sonic------Grilled Chicken Wrap w/out Ranch-------------38--------------------- 36
Sonic------Chicken Strip Wrap------------------------------- 55----------------------53
Sonic------Chicken Strip Wrap w/out Ranch---------------53----------------------51
Sonic------Fritos Chilli Cheese Wrap------------------------68----------------------63
posted by Anonymous
PermaLink @ 11:36 AM
Sonic------ Carb Friendly Tortilla------------------------------30---------------------15
Sonic------Carb Friendly Chicken Club Wrap---------------34---------------------18
Sonic------Diet Cherry Limeade - Large----------------------8-----------------------6
Sonic------Lime Wedge (each)---------------------------------2-----------------------1
Sonic------Cherry (each)----------------------------------------2-----------------------2
Sonic------No. 1 Sonic Burger---------------------------------43---------------------41
Sonic------No. 2 Sonic Burger---------------------------------43---------------------41
Sonic------No. 1 Sonic Cheeseburger-----------------------44----------------------42
Sonic------No. 2 Sonic Cheeseburger-----------------------44----------------------42
Sonic------Jr. Burger--------------------------------------------27-----------------------26
Sonic------Bacon Chedder Burger----------------------------60---------------------56
Sonic------Chicken Club Wrap---------------------------------75---------------------72
Sonic------Country Fried Steak Sandwich-------------------56---------------------54
Sonic------Chicken Strip Dinner-------------------------------86---------------------81
Sonic------Chicken Strip Snack--------------------------------22---------------------22
Sonic------Cherry Limeade - Large---------------------------96---------------------94
Sonic------Grilled Chicken Wrap------------------------------40---------------------38
Sonic------Grilled Chicken Wrap w/out Ranch-------------38--------------------- 36
Sonic------Chicken Strip Wrap------------------------------- 55----------------------53
Sonic------Chicken Strip Wrap w/out Ranch---------------53----------------------51
Sonic------Fritos Chilli Cheese Wrap------------------------68----------------------63
posted by Anonymous
PermaLink @ 11:36 AM
